1.04 UTF-8 0 0 0 a dificiency of phosphorylase kinase in th eliver should yeild what effects on the body? compared to a normal person liver glycogen after a meal would be ________ and blood glucose after a day-long fast ___________ 2 higher lower 1 one biochemical difference between a 96-hour fast and diabetes mellitus is that at the end of a fast.... in regards to the brain. 2 the brain has a limiting amount of glucose to serve as fuel 1 the major role of creatine kinase is to provide a direct souce of ___________ 2 ATP 1 many pesticides are uncouplers of oxidative phosphorylation. The structural basis for their uncoupling action is the fact that they: 2 are acids and both the acid and base forms are soluble in the lipid layer of membranes 1 lactose intolerance is due to a ____________ of _______________ in the ____________ 2 deficiency lactase intestine 1 arsnic is a poison because it can inhibit the enzyme ____________ 2 alpha-ketoglutarate dehydrogenase complex 1 in the glycogen cascae, when the catalytic activity of the enzyme ____________ is low, the catalytic activity of the enzyme _______________ is also low. 2 adenylate cyclase phosphorylase 1 the mafor souces of maetabolically synthesized glucose in the blood are __________ and _____________ 2 liver and kidney 1 the liver and the kidneys are the only tissues to contain considerable levels of what enzyme 2 glucose 6-phosphatase 1 viagra acts as a structural analog of ____________ 2 3',5'-cyclic-GMP 1 rotenone inhibits what enzyme? 2 NADH-coenzyme Q oxidoreductase (complex I) 1 ATP is synthesized on the ____________ side of the ____________ membrane 2 matrix inner mitochondrial 1 Protons spontaneously flow down a thermodynamic gradient form the ________ side to the ________ side of the ___________ to drive ATP synthesis 2 intermembrane space matrix inner mitochondrial membrane 1 the major role of glucose 6-phosphate dehydrogenase is to provide a direct source of ___________ 2 NADPH 1 a major role of glucose 6-phosphatase is to provide a direct souce of _________________ 2 glucose 1 a mojor role of alpha-ketoglutarate dehydrogenase is to provide a direct source of __________ 2 NADH 1 cyanide poisoning includes direct inhibition of what enzymes? 2 cytochrome oxidase (complex IV) 1 what is the most likely deficient enzyme for a pt with the following: developed seizures at age 3 months elevated lactic acidosis elevated pyruvic acidosis intermittent hypoglycemia and ketosis administration of alanine (a precursor of pyruvate) failed to elevate blood glucose 2 pyruvate carboxylase 1 a pt with malaria has a deficiency in activity of the enzyme glucose 6-phosphate dehydrogenase. what action do you want an administed drug to have? 2 decrease the levels of reduced glutathione in erythrocytes 1 ketone bodies acetoacetate ad 2-hydroxybutyrate ______________ 2 are energy sources for several tissues 1 beri beri is a deficiency of 2 thiamine 1 the enzyme thiaminase results in low catalytic activity of _____________ 2 the pyruvate dehydrogenase complex 1 if isoproterenol (in asthma sprays) is a beta-adrenergic agonist what would you expect it to do to the following: 1 phosphorylase 2 glycogen synthase 3 Protein kinase A 4 adenylate cyclase 2 increase decrease increase increase 1 people of East Asian decent become flushed at cocktail parties because they have lower activity of what enzyme? 2 aldehyde dehydrogenase 1