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sucrose has a __________ and a ____________membered ring and lactose has a ___________ and a _________ membered ring
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5 and 6
6 and 6
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floride is added to blood samples to prevent what?
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glycolysis
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what will inhibit enolase
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floride
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what are hemolytic anemias
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erythrocytes lyse due to decreased energy production
most common with pyruvate kinase deficiency
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what does a pyruvate kinase deficiency cause?
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hemolytic anemia
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what is the benefit of going from glucose to lactate
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you get two ATP
anaerobic
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what is an isozyme
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different enzyme that catalyzes the same rxn
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arnsic inhibits what complex
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alpha ketoglutarate dehydrogenase complex
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what inhibits alpha ketoglutarate dehydrogenase complex
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arsenic
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which is a stronger oxidyzing agent FAD or NAD
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FAD
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what are the three molecule that can cross the inner membrane of Mito w/o a transporter
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oxygen
carbon dioxide
water
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what is the purpose of the FeS centers
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transfer electrons
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complex IV is inhibited by what
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cyanide
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cyanide inhibits what complex
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complex IV of respiratory chain
cytochrome oxidase
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what is a cyanide antidote
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thiosulfate
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what does thiosulfate do?
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antidote for cyanide poisoning
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what is the definition of the Proton Motive Force
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energy released when H+ moves acrss the imm from the outside into the matrix
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how many H+ go through the F0 channel for one turn of F1
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10
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how many ATP are produced per turn of the F1 unit
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3.3
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what does the glycerol phosphate shuttle do?
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transfers e- from cytoplam from NADH to FAD in the imm
this is done b/c NADH can't cross imm
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what does Tenormin do?
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it is a beta blocker
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what is the starvation signal
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cAMP
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what does phosphodiesterase do?
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degrades cAMP
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what degrades cAMP
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phosphodiesterase
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how do we inactivate phosphorylase kinase a-P
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Protein Phosphotase
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what is the well fed signal?
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protein phosphotase
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what does Protein Kinase A do?
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it inactivates glycogen synthase by phosphorylating it
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what does adenylate kinase do?
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2ADP <--> ATP + AMP
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Biotin is a vitamin that is a __________ for several _____________ reactions
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cofactor
carboxylase
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gluconeogenesis only occurs in what two tissues?
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liver
kidney
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what enzyme will glucagon stimulate?
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Fructose 1,6-Bisphosphatase
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Fructose 1,6-Bisphosphatase is stimulated by what?
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Glucagon
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what is the starvation hormone?
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glucagon
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what is the well-fed hormone
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insulin
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what is the purpose of the Cori Cycle?
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to get lactate out of the muscle and into the liver
get glucose from the liver to the muscles
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what happens when there is a buildup of Fructose 1-P
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ATP levels drop
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what is galactosemia
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deficiency of galactokinase which converts Galactose and ATP to Gal -1-P
or
deficiency of Galactose 1-phosphate uridylyl transferase
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what does galactose 1 phosphate uridylyl transferase do?
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converts Galactose-1-P + UDP-Glucose ---> UDP-Galactose + Glucose 1-P
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acetaldehyde is a major contributer to what?
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a hangover
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